MLB Picks · September 25, 2026
Arizona Diamondbacks vs San Diego Padres
Strong Lean🐶 Dog of the Day
Arizona Diamondbacks ML
+114
72
/ 100
Starting Pitchers
Arizona Diamondbacks · Away
Brandon Pfaadt (RHP)
San Diego Padres · Home
TBD
AI Analysis
Arizona brings Brandon Pfaadt (ERA 3.72, WHIP 1.17) who is a quality arm against an unknown Padres starter. The Diamondbacks are on a 5-game winning streak and have been on fire offensively — 5.8 R/G over their last 10 games with a .294 AVG and .857 OPS. Multiple Arizona hitters are blazing hot (Perdomo, Arenado .423 L14 🔥, Moreno .364 L14 🔥, Vargas 🔥). San Diego is the better team season-long (89-70) with elite recent offense (6.0 R/G L10) but their TBD starter is a major unknown. At +114, Arizona offers positive value with a known quality arm and the best recent offensive form on the slate.
Concerns
- •Padres starter is TBD — San Diego could roll out an ace and flip the pitching edge
- •Padres offense scorching (6 R/G L10) and multiple hot bats (Tatis, Merrill, Bogaerts, Cronenworth)
- •San Diego is a stronger team overall (89-70 vs 85-74)
Factor Breakdown