MLB Picks · September 18, 2026

Chicago Cubs vs Cincinnati Reds

Lean
Cubs ML
-143
67
/ 100
Starting Pitchers
Chicago Cubs · Away
Clay Holmes (RHP)
Cincinnati Reds · Home
Chase Burns (RHP)
AI Analysis

Chase Burns is the clear pitching star here with a 2.80 ERA, 1.15 WHIP, and 181 K in 151.1 IP — an elite ace performance. However, the Cubs counter with Clay Holmes posting a strong 2.85 ERA and 1.15 WHIP, giving Chicago a meaningful pitching edge of their own. The decisive factor is Cincinnati's woeful offense: a .699 team OPS (lowest in this slate), 3.92 R/G, and an abysmal L10 stretch of just 2.8 R/G with a .212 average. The Reds are 2-8 in their last 10 and have multiple cold hitters, making it hard to see them doing much against Holmes. The Cubs lineup is better overall, with Pete Crow-Armstrong, Bregman (🔥), and Conforto (🔥) providing top-end firepower. The -143 price is a slight negative but acceptable given the offensive mismatch.

Concerns
  • •Burns is a genuine ace who can dominate any lineup
  • •Cubs hitting .248 vs RHP and several cold bats (Suzuki ❄️, P. Ramírez ❄️)
  • •Cubs own L10 is just 4-6, limiting confidence
  • •Price at -143 compresses value slightly
Factor Breakdown
Powered by AI scoring across 6 proprietary factors. For informational and entertainment purposes only — not financial or betting advice, and results are not guaranteed. Must be 21+ or the applicable minimum age in your jurisdiction to wager.
Gambling problem? Call 1-800-GAMBLER. · More resources on the About page.