MLB Picks · September 22, 2026
Minnesota Twins vs San Francisco Giants
Lean
Minnesota Twins ML
-135
67
/ 100
Starting Pitchers
Minnesota Twins · Away
Taj Bradley (RHP)
San Francisco Giants · Home
Anthony Molina (RHP)
AI Analysis
Taj Bradley has been one of the better starters in baseball this season (3.81 ERA, 1.23 WHIP, 199 K in 172.1 IP — elite strikeout numbers) facing Anthony Molina, who has only 28 IP in his career sample (4.18 ERA, 1.11 WHIP). The Giants are 65-92, among the worst teams in the majors, with a weak lineup showing very little power or plate discipline depth. Minnesota's splits vs RHP (.249/.738) work well against Molina, and the Twins have a meaningful quality gap over San Francisco. At -135, reasonable price for a clear pitching and team-quality edge.
Concerns
- •Twins only 4-6 in L10 and on a L1 streak
- •Minnesota L5 offense has been cold (3.7 R/G, .234 AVG, .642 OPS)
- •Molina's small sample (28 IP) is a major wildcard — could be better than numbers show
- •Giants hit RHP reasonably well at home (.252/.733)
- •Multiple cold bats in Twins lineup (Royce Lewis, Jeffers, Kreidler)
Factor Breakdown