MLB Picks · May 25, 2026

St. Louis Cardinals vs Milwaukee Brewers

Strong Lean
Brewers ML
-233
72
/ 100
Edge Score
Starting Pitchers
St. Louis Cardinals · Away
Matthew Liberatore (LHP)
Milwaukee Brewers · Home
Jacob Misiorowski (RHP)
AI Analysis

Misiorowski is a legitimate ace candidate — 1.89 ERA, 0.88 WHIP, and a massive 88 K in 57 IP (elite K-rate). The Cardinals counter with Liberatore who has a bloated 4.70 ERA and 1.55 WHIP. The key concern is the Brewers hit LHP poorly (.218/.625 vs LHP), which tempers the offensive edge. However, Misiorowski is dominant enough to carry this game alone, and the Brewers are 30-20 with the best team ERA on the slate (3.31). Milwaukee's hot hitters — Contreras (🔥, .345 L14), Bauers (🔥, .373 L14) — suggest lineup depth. STL's offense has cooled and Winn is ice cold (❄️).

Concerns
  • Brewers offense hits LHP badly (.218/.625) — a real matchup problem
  • Cardinals have multiple hot bats: Herrera (🔥), Burleson (🔥), Walker (.966 OPS)
  • STL's recent 5.0 R/G over last 5 games is excellent
  • Misiorowski could regress — elite ERA may not last the full season
Factor Breakdown
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