MLB Picks
MLB Picks — September 21, 2025
15 games on the slate
Today's slate
ATL @ DET
Spencer Strider vs Casey Mize
Comerica Park
ATH @ PIT
Mitch Spence vs Mike Burrows
PNC Park
NYY @ BAL
Cam Schlittler vs Kyle Bradish
Oriole Park at Camden Yards
CHC @ CIN
Jameson Taillon vs Andrew Abbott
Great American Ball Park
WSH @ NYM
Jake Irvin vs Sean Manaea
Citi Field
TOR @ KC
Trey Yesavage vs Michael Wacha
Kauffman Stadium
CLE @ MIN
Joey Cantillo vs Simeon Woods Richardson
Target Field
SD @ CWS
Michael King vs Sean Burke
Rate Field
MIL @ STL
Robert Gasser vs Matthew Liberatore
Busch Stadium
MIA @ TEX
Eury Pérez vs Merrill Kelly
Globe Life Field
LAA @ COL
Caden Dana vs Kyle Freeland
Coors Field
SF @ LAD
Trevor McDonald vs Emmet Sheehan
Dodger Stadium
PHI @ AZ
Ranger Suarez vs Eduardo Rodriguez
Chase Field
SEA @ HOU
Logan Gilbert vs Jason Alexander
Daikin Park
BOS @ TB
Connelly Early vs Joe Boyle
George M. Steinbrenner Field