MLB Picks
MLB Picks — April 21, 2026
15 games on the slate
Today's slate
HOU @ CLE
Ryan Weiss vs Parker Messick
Progressive Field
CIN @ TB
Chase Burns vs Steven Matz
Tropicana Field
STL @ MIA
Dustin May vs Chris Paddack
loanDepot park
MIL @ DET
Kyle Harrison vs Keider Montero
Comerica Park
ATL @ WSH
Reynaldo López vs Foster Griffin
Nationals Park
NYY @ BOS
Luis Gil vs Connelly Early
Fenway Park
MIN @ NYM
Simeon Woods Richardson vs Nolan McLean
Citi Field
BAL @ KC
Shane Baz vs Kris Bubic
Kauffman Stadium
PHI @ CHC
Jesús Luzardo vs Shota Imanaga
Wrigley Field
PIT @ TEX
Carmen Mlodzinski vs Kumar Rocker
Globe Life Field
SD @ COL
Randy Vásquez vs Jimmy Herget
Coors Field
TOR @ LAA
Patrick Corbin vs Jack Kochanowicz
Angel Stadium
ATH @ SEA
Jacob Lopez vs Luis Castillo
T-Mobile Park
CWS @ AZ
Sean Burke vs Merrill Kelly
Chase Field
LAD @ SF
Yoshinobu Yamamoto vs Landen Roupp
Oracle Park